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Interplay between S-Cyclin-dependent Kinase and Dbf4-dependent Kinase in Controlling DNA Replication through Phosphorylation of Yeast Mcm4 N-Terminal Domain

Cyclin-dependent (CDK) and Dbf4-dependent (DDK) kinases trigger DNA replication in all eukaryotes, but how these kinases cooperate to regulate DNA synthesis is largely unknown. Here, we show that budding yeast Mcm4 is phosphorylated in vivo during S phase in a manner dependent on the presence of fiv...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Devault, Alain, Gueydon, Elisabeth, Schwob, Etienne
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366871/
https://ncbi.nlm.nih.gov/pubmed/18321994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-06-0614
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