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A charged and contoured surface on the nucleosome regulates chromatin compaction
Local nucleosome-nucleosome interactions in cis drive chromatin folding, whereas interactions in trans lead to fiber-fiber oligomerization. Here we show that peptides derived from the histone H4 tail and Kaposi's sarcoma herpesvirus LANA protein can replace the endogenous H4 tail, resulting in...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366819/ https://ncbi.nlm.nih.gov/pubmed/17965723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1334 |
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