A charged and contoured surface on the nucleosome regulates chromatin compaction

Local nucleosome-nucleosome interactions in cis drive chromatin folding, whereas interactions in trans lead to fiber-fiber oligomerization. Here we show that peptides derived from the histone H4 tail and Kaposi's sarcoma herpesvirus LANA protein can replace the endogenous H4 tail, resulting in...

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Main Authors: Chodaparambil, Jayanth V, Barbera, Andrew J, Lu, Xu, Kaye, Kenneth M, Hansen, Jeffrey C, Luger, Karolin
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366819/
https://ncbi.nlm.nih.gov/pubmed/17965723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1334
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