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Mutually Exclusive Splicing of the Insect Dscam Pre-mRNA Directed by Competing Intronic RNA Secondary Structures

Drosophila Dscam encodes 38,016 distinct axon guidance receptors through the mutually exclusive alternative splicing of 95 variable exons. Importantly, known mechanisms that ensure the mutually exclusive splicing of pairs of exons cannot explain this phenomenon in Dscam. I have identified two classe...

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Autor principal: Graveley, Brenton R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2005
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366815/
https://ncbi.nlm.nih.gov/pubmed/16213213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2005.07.028
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