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Evolution of the oncogenic potential of v-rel: rel-induced expression of immunoregulatory receptors correlates with tumor development and in vitro transformation.

v-rel is a viral oncogene that evolved from turkey c-rel, an NF-kappa B-related transcription factor. Numerous structural alterations record the evolutionary selection of v-rel and distinguish it from c-rel. To evaluate the biological significance of these alterations, we constructed a set of five c...

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Publicat a:J Virol
Autors principals: Nehyba, J, Hrdlicková, R, Humphries, E H
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236677/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8138989/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.4.2039-2050.1994
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