Mutations which affect the inhibition of protein phosphatase 2A by simian virus 40 small-t antigen in vitro decrease viral transformation.
Three independent point mutations within residues 97 to 103 of the simian virus 40-small-t antigen (small-t) greatly reduced the ability of purified small-t to inhibit protein phosphatase 2A in vitro. These mutations affected the interaction of small-t antigen with the protein phosphatase 2A A subun...
שמור ב:
| הוצא לאור ב: | J Virol |
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| Principais autores: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology (ASM)
1994
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236626/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8107228/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.3.1675-1681.1994 |
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