Mutations which affect the inhibition of protein phosphatase 2A by simian virus 40 small-t antigen in vitro decrease viral transformation.

Three independent point mutations within residues 97 to 103 of the simian virus 40-small-t antigen (small-t) greatly reduced the ability of purified small-t to inhibit protein phosphatase 2A in vitro. These mutations affected the interaction of small-t antigen with the protein phosphatase 2A A subun...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Mungre, S, Enderle, K, Turk, B, Porrás, A, Wu, Y Q, Mumby, M C, Rundell, K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236626/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8107228/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.3.1675-1681.1994
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