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Insulin-Like Growth Factor (IGF) Binding Protein-4 Is Both a Positive and Negative Regulator of IGF Activity in Vivo

IGFs are required for normal prenatal and postnatal growth. Although actions of IGFs can be modulated by a family of IGF-binding proteins (IGFBPs) in vitro, these studies have identified a complicated pattern of stimulatory and inhibitory IGFBP effects, so that understanding relevant aspects of IGFB...

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Detalhes bibliográficos
Main Authors: Ning, Yun, Schuller, Alwin G. P., Conover, Cheryl A., Pintar, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366183/
https://ncbi.nlm.nih.gov/pubmed/18258685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0536
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