Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses.

We developed an in vitro assay for antibodies to hepatitis C virus (HCV) that bind to virions and prevent initiation of the replication cycle in susceptible cells in vitro. These antibodies therefore appear to be capable of neutralizing the virus. Using this assay and a standard inoculum of HCV of k...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Shimizu, Y K, Hijikata, M, Iwamoto, A, Alter, H J, Purcell, R H, Yoshikura, H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236605/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8107212/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.3.1494-1500.1994
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