Mapping the Genetic Architecture of Gene Expression in Human Liver

Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order disease traits. Therefore, identifying the molecular phenotypes that vary in response to changes in DNA a...

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Detalhes bibliográficos
Main Authors: Schadt, Eric E, Molony, Cliona, Chudin, Eugene, Hao, Ke, Yang, Xia, Lum, Pek Y, Kasarskis, Andrew, Zhang, Bin, Wang, Susanna, Suver, Christine, Zhu, Jun, Millstein, Joshua, Sieberts, Solveig, Lamb, John, GuhaThakurta, Debraj, Derry, Jonathan, Storey, John D, Avila-Campillo, Iliana, Kruger, Mark J, Johnson, Jason M, Rohl, Carol A, van Nas, Atila, Mehrabian, Margarete, Drake, Thomas A, Lusis, Aldons J, Smith, Ryan C, Guengerich, F. Peter, Strom, Stephen C, Schuetz, Erin, Rushmore, Thomas H, Ulrich, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365981/
https://ncbi.nlm.nih.gov/pubmed/18462017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060107
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