Interleukin-4 (IL-4) enhances and soluble interleukin-4 receptor (sIL-4R) inhibits histamine release from peripheral blood basophils and mast cells in vitro and in vivo

The aim of the study was to analyse the effect of interleukin-4 (IL-4) on allergen and anti-IgE mediated histamine release from basophils and human skin mast cells and to assess whether soluble recombinant interleukin-4 receptor (sIL4R) can inhibit these effects. Anti-IgE stimulated histamine releas...

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Bibliographic Details
Main Authors: Niggemann, B., Zuberbier, T., Herz, U., Enssle, K., Wahn, U., Renz, H.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365851/
https://ncbi.nlm.nih.gov/pubmed/18472844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09629359791802
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