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IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils

IL-18 is a proinflammatory cytokine that plays an important role in natural killer cell activation and T helper 1 (Th1) cell responses. Mast cells and basophils are major inducers and effectors of allergic inflammation. Here we show that basophils and mast cells derived by culture of bone marrow cel...

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Detalhes bibliográficos
Main Authors: Yoshimoto, Tomohiro, Tsutsui, Hiroko, Tominaga, Kouji, Hoshino, Katsuaki, Okamura, Haruki, Akira, Shizuo, Paul, William E., Nakanishi, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24173/
https://ncbi.nlm.nih.gov/pubmed/10570181
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