Tumor-Associated Embryonic Antigen-Expressing Vaccines that Target CCR6 Elicit Potent CD8(+) T Cell-Mediated Protective and Therapeutic Antitumor Immunity

Despite its potency, the wider use of immunotherapy for B cell malignancies is hampered by the lack of well-defined tumor-specific Ags. In this study, we demonstrate that an evolutionarily conserved 37-kDa immature laminin receptor protein (OFA-iLRP), a nonimmunogenic embryonic Ag expressed by a var...

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Autores principales: Biragyn, Arya, Schiavo, Roberta, Olkhanud, Purevdorj, Sumitomo, Kenya, King, Alan, McCain, Megan, Indig, Fred E., Almanzar, Giovanni, Baatar, Dolgor
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365706/
https://ncbi.nlm.nih.gov/pubmed/17617631
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