Sequence specificity of furin, a proprotein-processing endoprotease, for the hemagglutinin of a virulent avian influenza virus.

The virulence of avian influenza viruses correlates with the sensitivity of their hemagglutinin (HA) to cellular proteases. Furin, a proprotein-processing subtilisin-related endoprotease, is a leading candidate for the enzyme that cleaves the HA of virulent avian viruses. We therefore compared the s...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Walker, J A, Molloy, S S, Thomas, G, Sakaguchi, T, Yoshida, T, Chambers, T M, Kawaoka, Y
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236564/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289354/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.2.1213-1218.1994
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