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Sequence specificity of furin, a proprotein-processing endoprotease, for the hemagglutinin of a virulent avian influenza virus.

The virulence of avian influenza viruses correlates with the sensitivity of their hemagglutinin (HA) to cellular proteases. Furin, a proprotein-processing subtilisin-related endoprotease, is a leading candidate for the enzyme that cleaves the HA of virulent avian viruses. We therefore compared the s...

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Autors principals: Walker, J A, Molloy, S S, Thomas, G, Sakaguchi, T, Yoshida, T, Chambers, T M, Kawaoka, Y
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC236564/
https://ncbi.nlm.nih.gov/pubmed/8289354
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