Sequences present in the cytoplasmic domain of CD4 are necessary and sufficient to confer sensitivity to the human immunodeficiency virus type 1 Vpu protein.

Míreanna Comhchosúla

• Human immunodeficiency virus type 1 Vpu protein induces degradation of CD4 in vitro: the cytoplasmic domain of CD4 contributes to Vpu sensitivity.
  le: Chen, M Y, et al.
  Foilsithe: (1993)
• The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradation.
  le: Bour, S, et al.
  Foilsithe: (1995)
• The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu function
  le: Kluge, Silvia F, et al.
  Foilsithe: (2013)
• Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4.
  le: Willey, R L, et al.
  Foilsithe: (1992)
• The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase.
  le: Stein, P H, et al.
  Foilsithe: (1994)