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Increase in soluble CD4 binding to and CD4-induced dissociation of gp120 from virions correlates with infectivity of human immunodeficiency virus type 1.

Mutations in the human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins gp120 and gp41, previously shown to confer an enhanced replicative capacity and broadened host range to the ELI1 strain of HIV-1, were analyzed for their biochemical effects on envelope structure and function. The te...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Willey, R L, Martin, M A, Peden, K W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236541/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7904656/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.2.1029-1039.1994
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