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A structural census of the current population of protein sequences

We examine the occurrence of the ≈300 known protein folds in different groups of organisms. To do this, we characterize a large fraction of the currently known protein sequences (≈140,000) in structural terms, by matching them to known structures via sequence comparison (or by secondary-structure cl...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Gerstein, Mark, Levitt, Michael
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9342336/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.22.11911
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