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A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain

Alterations in sodium channel expression and function have been suggested as a key molecular event underlying the abnormal processing of pain after peripheral nerve or tissue injury. Although the relative contribution of individual sodium channel subtypes to this process is unclear, the biophysical...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Porreca, Frank, Lai, Josephine, Bian, Di, Wegert, Sandra, Ossipov, Michael H., Eglen, Richard M., Kassotakis, Laura, Novakovic, Sanja, Rabert, Douglas K., Sangameswaran, Lakshmi, Hunter, John C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1999
Matèries:
Colloquium Paper
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33594/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10393873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.14.7640
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