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Characterization of mutants of human immunodeficiency virus type 1 that have escaped neutralization by a monoclonal antibody to the gp120 V2 loop.

The biologically cloned human immunodeficiency virus type 1 (HIV-1) RF isolate is sensitive to neutralization by the murine monoclonal antibody (MAb) G3-4 to a conformationally sensitive epitope in the V2 loop of HIV-1 gp120. To assess how variation in the V2 amino acid sequence affects neutralizati...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Yoshiyama, H, Mo, H, Moore, J P, Ho, D D
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1994
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236535/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7507188/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.2.974-978.1994
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