Neutralizing Antibodies from the Sera of Human Immunodeficiency Virus Type 1-Infected Individuals Bind to Monomeric gp120 and Oligomeric gp140

Antibodies that neutralize primary isolates of human immunodeficiency virus type 1 (HIV-1) appear during HIV-1 infection but are difficult to elicit by immunization with current vaccine products comprised of monomeric forms of HIV-1 envelope glycoprotein gp120. The limited neutralizing antibody resp...

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Main Authors: Stamatos, Nicholas M., Mascola, John R., Kalyanaraman, Vaniambadi S., Louder, Mark K., Frampton, Lynn M., Birx, Deborah L., VanCott, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Viral Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110475/
https://ncbi.nlm.nih.gov/pubmed/9811699
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