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Turnour necrosis factor stimulates endothelin-1 gene expression in cultured bovine endothelial cells

We have studied the effect of human recombinant tumour necrosis factor-α (TNF-α) on gene expression and production of endothelin-1 in cultured bovine aortic endothelial cells. TNF-α (10 and 100 ng ml(−1)) increased in a time dependent manner the preproendothelin-1 mRNA levels in respect to unstimula...

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Detalhes bibliográficos
Main Authors: Orisio, Silvia, Morigi, Marina, Zoja, Carla, Perico, Norberto, Remuzzi, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365346/
https://ncbi.nlm.nih.gov/pubmed/18475471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/S0962935192000401
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