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Kinetic Model for the Coupling between Allosteric Transitions in GroEL and Substrate Protein Folding and Aggregation
The bacterial chaperonin GroEL and the co-chaperonin GroES assist in the folding of a number of structurally unrelated substrate proteins (SPs). In the absence of chaperonins, SP folds by the kinetic partitioning mechanism (KPM) according to which a fraction of unfolded molecules reaches the native...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2364733/ https://ncbi.nlm.nih.gov/pubmed/18313071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.01.059 |
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