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Global Amine and Acid Functional Group Modification of Proteins
A sequential reaction methodology is employed for the complete derivatization of protein thiols, amines, and acids in high purity under denaturing conditions. Following standard thiol alkylation, protein amines are modified via reductive methylation with formaldehyde and pyridine-borane. Protein aci...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2364710/ https://ncbi.nlm.nih.gov/pubmed/18184016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac7019317 |
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