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Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation

Mechanisms that control vascular smooth muscle cell (SMC) differentiation are poorly understood. We identify Pitx2 as a previously unknown homeodomain transcription factor that is rapidly induced in an in vitro model of SMC differentiation from multipotent stem cells. Pitx2 induces expression of mul...

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Autori principali: Shang, Yueting, Yoshida, Tadashi, Amendt, Brad A., Martin, James F., Owens, Gary K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364692/
https://ncbi.nlm.nih.gov/pubmed/18458156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200711145
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