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A Subanalgesic Dose of Morphine Eliminates Nalbuphine Anti-analgesia in Postoperative Pain

The agonist-antagonist kappa-opioid nalbuphine administered for postoperative pain produces greater analgesia in females than in males. In fact, males administered nalbuphine (5 mg) experience pain greater than those receiving placebo, suggesting the existence of an anti-analgesic effect. These sexu...

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Bibliografiska uppgifter
Huvudupphovsmän: Gear, Robert W., Gordon, Newton C., Hossaini-Zadeh, Mehran, Lee, Janice S., Miaskowski, Christine, Paul, Steven M., Levine, Jon D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364600/
https://ncbi.nlm.nih.gov/pubmed/18201935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2007.11.011
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