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A Subanalgesic Dose of Morphine Eliminates Nalbuphine Anti-analgesia in Postoperative Pain

The agonist-antagonist kappa-opioid nalbuphine administered for postoperative pain produces greater analgesia in females than in males. In fact, males administered nalbuphine (5 mg) experience pain greater than those receiving placebo, suggesting the existence of an anti-analgesic effect. These sexu...

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書誌詳細
主要な著者: Gear, Robert W., Gordon, Newton C., Hossaini-Zadeh, Mehran, Lee, Janice S., Miaskowski, Christine, Paul, Steven M., Levine, Jon D.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364600/
https://ncbi.nlm.nih.gov/pubmed/18201935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2007.11.011
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