Characterization of the MUC1.Tg/MIN Transgenic Mouse as a Model for Studying Antigen-Specific Immunotherapy of Adenomas

A bigenic MUC1.Tg/MIN mouse model was developed by crossing Apc/(MIN/+) (MIN) mice with human MUC1 transgenic mice to evaluate MUC1 antigen-specific immunotherapy of intestinal adenomas. The MUC1.Tg/MIN mice developed adenomas at a rate comparable to that of MIN mice and had similar levels of serum...

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Main Authors: Akporiaye, Emmanuel T., Bradley-Dunlop, Deborah, Gendler, Sandra J., Mukherjee, Pinku, Madsen, Cathy S., Hahn, Tobias, Besselsen, David G., Dial, Sharon M., Cui, Haiyan, Trevor, Katrina
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364598/
https://ncbi.nlm.nih.gov/pubmed/17707958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.06.063
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