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Vaccine therapy for ocular herpes simplex virus (HSV) infection: periocular vaccination reduces spontaneous ocular HSV type 1 shedding in latently infected rabbits.

Periocular vaccination of rabbits with preexisting herpes simplex virus type 1 (HSV-1) latent infection with recombinant HSV-2 glycoproteins B and D (gB2 and gD2) plus adjuvant significantly reduced ocular viral shedding. Rabbits were infected in both eyes with HSV-1 strain McKrae. Following HSV-1 i...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Nesburn, A B, Burke, R L, Ghiasi, H, Slanina, S, Bahri, S, Wechsler, S L
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1994
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236451/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8035508/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.8.5084-5092.1994
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