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Role of proteolytic enzymes in human prostate bone metastasis formation: in vivo and in vitro studies

Prostate cancers ability to invade and grow in bone marrow stroma is thought to be due in part to degradative enzymes. The formation of prostate skeletal metastases have been reproduced in vitro by growing co-cultures of prostatic epithelial cells in bone marrow stroma. Expression of urokinase plasm...

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Detalhes bibliográficos
Main Authors: Hart, C A, Scott, L J, Bagley, S, Bryden, A A G, Clarke, N W, Lang, S H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364179/
https://ncbi.nlm.nih.gov/pubmed/11953862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600207
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