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Mechanism of action for N-substituted benzamide-induced apoptosis

We have analysed the mechanism of action for induction of apoptosis by N-substituted benzamides using declopramide as a lead compound. We show here that declopramide at doses above 250 μM in the mouse 70Z/3 pre-B cell line or in the human promyeolocytic cancer cell line HL60 induced cytochrome c rel...

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Autori principali: Olsson, A R, Lindgren, H, Pero, R W, Leanderson, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364155/
https://ncbi.nlm.nih.gov/pubmed/11953831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600136
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