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Reduction of Amphotericin B-Induced Renal Tubular Apoptosis by N-Acetylcysteine

The reduction of amphotericin B (AmB)-induced renal tubular apoptosis and nephrotoxicity by N-acetylcysteine (NAC) in a murine model was evaluated. Four groups of rats were treated with AmB for 5 days, and each group concomitantly received two doses of 30, 60, or 120 mg of NAC/kg of body weight/day...

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Bibliografiske detaljer
Main Authors: Odabasi, Z., Karaalp, A., Cermik, H., Mohr, J., Tigen, E. T., Koc, M., Korten, V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704667/
https://ncbi.nlm.nih.gov/pubmed/19414577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00001-09
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