In vitro anti-tumour activity of α-galactosylceramide-stimulated human invariant Vα24+NKT cells against melanoma

α-galactosylceramide (KRN 7000, α-GalCer) has shown potent in vivo anti-tumour activity in mice, including against melanoma and the highly specific effect of inducing proliferation and activation of human Vα24+NKT-cells. We hypothesized that human Vα24+NKT-cells activated by α-GalCer might exhibit a...

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Hlavní autoři: Kikuchi, A, Nieda, M, Schmidt, C, Koezuka, Y, Ishihara, S, Ishikawa, Y, Tadokoro, K, Durrant, S, Boyd, A, Juji, T, Nicol, A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2001
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364120/
https://ncbi.nlm.nih.gov/pubmed/11531261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1973
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