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Frequent loss of expression without sequence mutations of the DCC gene in primary gastric cancer

Loss of heterozygosity (LOH) on chromosome 18q21 is frequently found in various human cancers, suggesting the presence of tumour suppressor gene(s) in this chromosomal region. DCC is the most likely target of LOH because loss or reduction of DCC expression has been found in many types of cancers. Ho...

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Détails bibliographiques
Auteurs principaux: Sato, K, Tamura, G, Tsuchiya, T, Endoh, Y, Usuba, O, Kimura, W, Motoyama, T
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364029/
https://ncbi.nlm.nih.gov/pubmed/11461076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1888
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