Tyrphostin AG 1024 modulates radiosensitivity in human breast cancer cells

Insulin-like growth factor-1 (IGF-1) plays an important growth-promoting effect by activating the PI3K/Akt signalling pathway, inhibiting apoptotic pathways and mediating mitogenic actions. Tyrphostin AG 1024, one selective inhibitor of IGF-1R, was used to evaluate effects on proliferation, radiosen...

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Dettagli Bibliografici
Autori principali: Wen, B, Deutsch, E, Marangoni, E, Frascona, V, Maggiorella, L, Abdulkarim, B, Chavaudra, N, Bourhis, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2001
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Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364012/
https://ncbi.nlm.nih.gov/pubmed/11747348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2171
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