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Topical administration of a doxorubicin-specific monoclonal antibody prevents drug-induced mouth apoptosis in mice
One of the most severe side effects of anti-tumour chemotherapy is mucositis due to drug toxicity for rapidly dividing cells. We show here that anti-DXR monoclonal antibodies can prevent DXR-induced damage. Indeed, apoptosis, confined to the proliferative compartment of the basal mucosa, observed in...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2364005/ https://ncbi.nlm.nih.gov/pubmed/11747341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2188 |
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