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A parathyroid-hormone-related-protein (PTH-rP)-specific cytotoxic T cell response induced by in vitro stimulation of tumour-infiltrating lymphocytes derived from prostate cancer metastases, with epitope peptide-loaded autologous dendritic cells and low-dose IL-2

Bone metastases are one of the most common events in patients with prostate carcinoma. PTH-rP, a protein produced by prostate carcinoma and other epithelial cancers, is a key agent for the development of bone metastases. A PTH-rP-derived peptide, designated PTR-4 was identified, which is capable to...

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Detalhes bibliográficos
Main Authors: Correale, P, Micheli, L, Vecchio, M T Del, Sabatino, M, Petrioli, R, Pozzessere, D, Marsili, S, Giorgi, G, Lozzi, L, Neri, P, Francini, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363980/
https://ncbi.nlm.nih.gov/pubmed/11742494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2136
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