Anti-Her-2/neu antibody induces apoptosis in Her-2/neu overexpressing breast cancer cells independently from p53 status

Anti-Her-2/neu antibody is known to induce apoptosis in HER-2/neu overexpressing breast cancer cells. However, exact regulatory mechanisms mediating and controlling this phenomenon are still unknown. In the present study, we have investigated the effect of anti-Her-2/neu antibody on apoptosis of HER...

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Hlavní autoři: Brodowicz, T, Kandioler, D, Tomek, S, Ludwig, C, Rudas, M, Kunstfeld, R, Koestler, W, Hejna, M, Budinsky, A, Wiltschke, C, Zielinski, C C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2001
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363971/
https://ncbi.nlm.nih.gov/pubmed/11742500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2197
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