DNA Hypermethylation, Her-2/neu Overexpression and p53 Mutations in Ovarian Carcinoma

OBJECTIVES: To define patterns of aberrant DNA methylation, p53 mutation and Her-2/neu overexpression in tissues from benign (N=29), malignant (N=100), and border line malignant ovaries (N=10), as compared to normal (N=68) ovarian tissues. Further, to explore the relationship between the presence of...

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Main Authors: Feng, Qinghua, Deftereos, Georgios, Hawes, Stephen E., Stern, Joshua E., Willner, Julia B, Swisher, Elizabeth M, Xi, Longfu, Drescher, Charles, Urban, Nicole, Kiviat, Nancy
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642648/
https://ncbi.nlm.nih.gov/pubmed/18757082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2008.07.036
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