Tcf-3 expression and β -catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour)

Aggressive fibromatosis harbours mutations resulting in β-catenin protein stabilization. Primary cell cultures demonstrate constitutive tcf activation in aggressive fibromatosis. Expression and co-immunoprecipitation studies suggest that β-catenin binds and activates tcf-3 in this tumour. This is th...

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Detalhes bibliográficos
Main Authors: Tejpar, S, Li, C, Yu, C, Poon, R, Denys, H, Sciot, R, Cutsem, E Van, Cassiman, J J, Alman, B A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363921/
https://ncbi.nlm.nih.gov/pubmed/11437409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1857
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