A phase I study in paediatric patients to evaluate the safety and pharmacokinetics of SPI-77, a liposome encapsulated formulation of cisplatin

Pre-clinical studies indicate that cisplatin encapsulated in STEALTH®liposomes (SPI-77) retains anti-tumour activity, but has a much reduced toxicity, compared to native cisplatin. A phase I study was conducted to determine the toxicity and pharmacokinetics of SPI-77 administered to children with ad...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Veal, G J, Griffin, M J, Price, E, Parry, A, Dick, G S, Little, M A, Yule, S M, Morland, B, Estlin, E J, Hale, J P, Pearson, A D J, Welbank, H, Boddy, A V
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2001
Предметы:
Regular Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363870/
https://ncbi.nlm.nih.gov/pubmed/11308249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1723
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы