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Cleavage of caspases-1, -3, -6, -8 and -9 substrates by proteases in skeletal muscles from mice undergoing cancer cachexia

A prominent feature of several type of cancer is cachexia. This syndrome causes a marked loss of lean body mass and muscle wasting, and appears to be mediated by cytokines and tumour products. There are several proteases and proteolytic pathways that could be responsible for the protein breakdown. I...

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Bibliografiska uppgifter
Huvudupphovsmän: Belizário, J E, Lorite, M J, Tisdale, M J
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2001
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363854/
https://ncbi.nlm.nih.gov/pubmed/11308266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1700
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