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A probability model for predicting BRCA1 and BRCA2 mutations in breast and breast-ovarian cancer families

Germline mutations in BRCA1 and BRCA2 genes predispose to hereditary breast and ovarian cancer. Our aim was to find associations between the clinical characteristics and positive mutation status in 148 breast cancer families in order to predict the probability of finding a BRCA mutation in a family....

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Vahteristo, P, Eerola, H, Tamminen, A, Blomqvist, C, Nevanlinna, H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2001
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363799/
https://ncbi.nlm.nih.gov/pubmed/11237395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1626
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