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The frequency of the predominant Jewish mutations in BRCA1 and BRCA2 in unselected Ashkenazi colorectal cancer patients

It is presently unclear whether carriers of BRCA1 mutations have an increased risk for colorectal cancer (CRC). To gain insight into this issue, 225 unselected Ashkenazi Jewish CRC patients were tested for the presence of the three common Jewish BRCA1/2 germline mutations: 185delAG and 5382insC (BRC...

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Detalhes bibliográficos
Main Authors: Chen-Shtoyerman, R, Figer, A, Fidder, H H, Rath, P, Yeremin, L, Meir, S Bar, Friedman, E, Theodor, L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363769/
https://ncbi.nlm.nih.gov/pubmed/11207040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1598
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