The frequency of the predominant Jewish mutations in BRCA1 and BRCA2 in unselected Ashkenazi colorectal cancer patients

It is presently unclear whether carriers of BRCA1 mutations have an increased risk for colorectal cancer (CRC). To gain insight into this issue, 225 unselected Ashkenazi Jewish CRC patients were tested for the presence of the three common Jewish BRCA1/2 germline mutations: 185delAG and 5382insC (BRC...

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Bibliografiske detaljer
Main Authors: Chen-Shtoyerman, R, Figer, A, Fidder, H H, Rath, P, Yeremin, L, Meir, S Bar, Friedman, E, Theodor, L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363769/
https://ncbi.nlm.nih.gov/pubmed/11207040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1598
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