Loss of heterozygosity in the Hodgkin-Reed Sternberg cell line L1236

Hodgkin-Reed Sternberg cells are derived from germinal centre B-cells in most cases. Somatic mutations affecting their rearranged immunoglobulin genes were detected, rendering potential functional rearrangements non-functional. Under physiological conditions such cells would be designated to undergo...

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Dettagli Bibliografici
Autori principali: Staratschek-Jox, A, Thomas, R Kurt, Zander, T, Massoudi, N, Kornacker, M, Bullerdiek, J, Fonatsch, C, Diehl, V, Wolf, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2001
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Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363750/
https://ncbi.nlm.nih.gov/pubmed/11161403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1593
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