Constitutive Expression of c-FLIP in Hodgkin and Reed-Sternberg Cells

Crosslinking of the transmembrane receptor CD95/Fas leads to activation of a signaling cascade resulting in apoptosis. c-FLIP is a recently described protein that potently inhibits Fas-mediated apoptosis and has been shown to be a key factor in germinal center B cell survival. Because Hodgkin and Re...

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Bibliographische Detailangaben
Hauptverfasser: Thomas, Roman Kurt, Kallenborn, Anne, Wickenhauser, Claudia, Schultze, Joachim Ludwig, Draube, Andreas, Vockerodt, Martina, Re, Daniel, Diehl, Volker, Wolf, Jürgen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2002
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867202/
https://ncbi.nlm.nih.gov/pubmed/11943736
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