c-FLIP Mediates Resistance of Hodgkin/Reed-Sternberg Cells to Death Receptor–induced Apoptosis

Resistance to death receptor–mediated apoptosis is supposed to be important for the deregulated growth of B cell lymphoma. Hodgkin/Reed-Sternberg (HRS) cells, the malignant cells of classical Hodgkin's lymphoma (cHL), resist CD95-induced apoptosis. Therefore, we analyzed death receptor signalin...

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Hlavní autoři: Mathas, Stephan, Lietz, Andreas, Anagnostopoulos, Ioannis, Hummel, Franziska, Wiesner, Burkhard, Janz, Martin, Jundt, Franziska, Hirsch, Burkhard, Jöhrens-Leder, Korinna, Vornlocher, Hans-Peter, Bommert, Kurt, Stein, Harald, Dörken, Bernd
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211891/
https://ncbi.nlm.nih.gov/pubmed/15078899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031080
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