Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: relationship to the tissuenhibitors of metalloproteinases and membrane type-1-matrix metalloproteinase

The matrix metalloproteinases, MMP-2 and MMP-9, are capable of degrading components of the basement membrane, a vital barrier breached during the progression of colorectal cancer. The regulation of MMP-2 activation and subsequent targets is vital to understanding the metastatic process. MMP-2 was no...

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Bibliografiske detaljer
Main Authors: Collins, H M, Morris, T M, Watson, S A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363688/
https://ncbi.nlm.nih.gov/pubmed/11401321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1831
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