Overexpression of Matrix Metalloproteinase-10 and Matrix Metalloproteinase-3 in Human Diabetic Corneas : A Possible Mechanism of Basement Membrane and Integrin Alterations

We have previously described decreased immunostaining of nidogen-1/entactin; laminin chains α1, α5, β1,γ1; and epithelial integrin α(3)β(1) in human diabetic retinopathy (DR) corneas. Here, using 142 human corneas, we tested whether these alterations might be caused by decreased gene expression leve...

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Detalhes bibliográficos
Main Authors: Saghizadeh, Mehrnoosh, Brown, Donald J., Castellon, Raquel, Chwa, Marilyn, Huang, Gang H., Ljubimova, Julia Y., Rosenberg, Shari, Spirin, Konstantin S., Stolitenko, Raisa B., Adachi, Wakako, Kinoshita, Shigeru, Murphy, Gillian, Windsor, L. Jack, Kenney, M. Cristina, Ljubimov, Alexander V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850323/
https://ncbi.nlm.nih.gov/pubmed/11159210
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