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A randomized trial of 13-Cis retinoic acid in children with advanced neuroblastoma after high-dose therapy
One hundred and seventy-five children with Stage 3 or 4 neuroblastoma who had obtained a good response to conventional therapy were randomly allocated to 13-Cis retinoic acid at a dose of 0.75 mg/kg/day or placebo for up to 4 years. Toxicity was mild but no advantage in event-free survival was shown...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2000
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363577/ https://ncbi.nlm.nih.gov/pubmed/11027423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1425 |
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