Subclonal components of consensus fitness in an RNA virus clone.

Most RNA virus populations exhibit extremely high mutation frequencies which generate complex, genetically heterogeneous populations referred to as quasi-species. Previous work has shown that when a large spectrum of the quasi-species is transferred, natural selection operates, leading to eliminatio...

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Опубликовано в::	J Virol
Главные авторы:	Duarte, E A, Novella, I S, Ledesma, S, Clarke, D K, Moya, A, Elena, S F, Domingo, E, Holland, J J
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1994
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236352/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8207804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.7.4295-4301.1994
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