Subclonal components of consensus fitness in an RNA virus clone.

Most RNA virus populations exhibit extremely high mutation frequencies which generate complex, genetically heterogeneous populations referred to as quasi-species. Previous work has shown that when a large spectrum of the quasi-species is transferred, natural selection operates, leading to eliminatio...

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Main Authors: Duarte, E A, Novella, I S, Ledesma, S, Clarke, D K, Moya, A, Elena, S F, Domingo, E, Holland, J J
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC236352/
https://ncbi.nlm.nih.gov/pubmed/8207804
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